Research in applied cardiopulmonary physiology and extracorporeal support

Mechanical power during ECCO2R

We have published this year at the ISICEM an abstract about mechanical power ​1​ and its reduction during extracorporeal CO2 removal. We have found that the optimal combination of tidal volume and frequency might be different than currently proposed strategies ​2​. We show that an increase in needed ventilation due to a higher VCO2 is […]

Don’t go for the sats – physiological note on Oxygenation in COVID-19

Background A lot of discussion has been going about oxygenation in COVID-19 and when to intubate patients​1​. The question ultimately becomes, when to intubate. Patients without distress, high work of breathing or risk of self inflicted lung injury probably should not be intubated ​2​. Hypoxia can be tolerated up to a very low point. Of […]

How the right heart copes with venous return – was Frank Starling wrong all along?

We have recently published a paper exploring thermodilution methods during veno-arterial extracorporeal membrane oxygenation (VA ECMO) ​1​. (Watch Video here). Traditionally, thermodilution methods have been the gold standard for cardiac output measurement. During the setting of VA ECMO, indicator or injectate gets sucked into the ECMO limb and gets passed into the pulmonary artery; therefore, […]

Welcome to

Our study group conducts experimental studies to answer fundamental questions of hemodynamics and to investigate physiological phenomena during extracorporeal therapy. Our experiments are performed at the Department of Intensive Care Medicine, Inselspital Bern. On this site we will Blog on interesting techniques, approaches and publications. PhysiologyResearch.Com Team Kaspar Bachmann David Berger Per Werner Möller Photo by Piron Guillaume on Unsplash. Site Icon […]